The 12th International Workshop on Multi-Level Modeling (MULTI 2025) has been accepted as part of this year’s ACM/IEEE International Conference on Model-Driven Engineering Languages and Systems (MoDELS 2025). The conference will take place at the University of Michigan in Ann Arbor, United States. The workshop is co-organized by our team member Pierre Maier. MULTI is the main forum for multi-level-modeling researchers and practitioners. Participants discuss new research results, tools, and application areas. Further information on the workshop as well as submission requirements are available on the workshop website MULTI 2025.